ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

GUINEA PIG DANDER ALLERGY


Key Allergens

There is are 5 allergens associated with an allergy to guinea pigs, this includes their hair, dander (which is flakes of dry skin), urine and saliva. These are all allergens associated with airways.

4 of the allergens are lipocalin proteins, in other animal dander allergies this is the protein that most individuals react to. These proteins transport molecules like lipids and steroids around the body.

Cav p 4 is a serum albumin protein, people who are allergic to this protein are more likely to be allergic to other mammals and very rarely can become allergic to eating mammalian meats such as beef, chicken and pork, which also contain these proteins.

Associated Syndromes

Allergy to guinea pig dander is strongly strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.

Guinea pig contains serum albumin as an inhalant allergen, this is a protein which can cause problems for people with Alpha Gal Syndrome. Guinea pigs are most often eaten in Peru (where they are called "cuy") and should be avoided if suffering from this allergic syndrome.

Cross Reactivity

A guinea pig allergy can be strongly linked to other animal allergies due to the lipocalin proteins. There is evidence of cross reactivity due to this protein with cockroaches, cows, dogs, hamsters, horses, cats, mice, rabbits and rats.

Other animals whose hair contains serum albumin proteins as an airbourne allergen include dog, horse, cat and mouse danders. Serum albumin is also found as a food allergen in beef, chicken and pork.

Resources

Websites

Allergen Encyclopedia - Guinea Pig

Science Direct - Lipocalin

Pet Finder - Living With Guinea Pig Allergies


Articles and Journals

Component-resolved diagnosis using guinea-pig allergens elucidates allergen sensitization profiles in allergy to furry animals, 2021

Anaphylaxis induced by inhaling guinea pig allergen, 2021

Dog keeping at home before and during pregnancy decreased the risk of food allergy in 1-year-old children, 2020

Exotic pet allergy, 2019

Diagnosis of Allergy to Mammals and Fish: Cross-Reactive vs. Specific Markers, 2017

Allergy to uncommon pets: new allergies but the same allergens, 2013

Evaluation of two new recombinant guinea-pig lipocalins, Cav p 2 and Cav p 3, in the diagnosis of guinea-pig allergy, 2011

Severe allergic reactions to guinea pig, 2005

Purification and partial characterization of the major allergen, Cav p 1, from guinea pig Cavia porcellus, 2002



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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