Key Allergens

This page only relates to eggs - if you are interested in allergy to chicken you can visit that page HERE. Chicken eggs contain a lot of allergenic proteins and can cause very severe allergic reactions, as such they are on the EU list of 14 allergens which need to be declared in packaging.

There are 10 allergens associated with bird eggs, 4 of them are specifically linked to egg whites and the others are linked to egg yolk.

Egg yolk contains the allergen serum albumin, which is also found in meats and mammalian milks. This explains the small number of people who are allergic to both eggs and cow’s milk.

Eggs also contain aldolase and enolase proteins; these are considered to be minor panallergens. These proteins are resistant to heat, so survive cooking and processing, meaning they are still able to cause allergic reactions.

Chickens and eggs also both contain parvalbumin proteins, which are also found in most species of fish.

Food Intolerances

Food is low in histamine Food is moderate in sulphites Food is low in FODMAP Food is low in salicylates Food is low in lectin

Fresh eggs are perfect for most food intolerances as they are low across the board.

Eggs are a low FODMAP food. FODMAP stands for Fermentable oligosaccharides, disaccharides, monosaccharides and polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.

Salicylates are phenolic compounds found in plants with the potential to cause gastrointestinal food intolerance symptoms in people who are sensitive to salicylates. As eggs are from an animal sources they are completely free of salicylates.

Pickled or preserved eggs are moderate in sulphites, but are OK fresh. Sulphites are inorganic salts used in preservations and have the potential to cause symptoms of food intolerance to those sensitive to sulphites, this food intolerance is more common in asthmatics. An improvement in symptoms can be made with a change to a low sulphite diet.

You can read more about Food Intolerances on the dedicated Food Intolerance Page.

Associated Syndromes

An allergy to egg can sometimes be associated with an allergy to chicken, this is called Bird-Egg Syndrome. In these cases sensitivity to egg is to the proteins in egg yolk, alpha livetin (gal d 5), which is found in both chickens and eggs.

Cross Reactivity

There is high cross reactivity with bird eggs from other species, such as duck, turkey and goose as they all have a similar composition of proteins.

Egg allergy is seen sometimes in patients who suffer from a chicken food allergy and also in combination with a fish allergy.

Other foods containing aldolase and enolase proteins include chicken, cod, catfish, salmon and tuna.

Beef, chicken and pork are other foods containing serum albumin proteins.

You can download an Egg Allergy Factsheet from the Allergy Resources Ko-fi Shop for just $0.50 (£0.40 or €0.45). This has up to date information on which foods contain linked allergens and what foods to avoid if you think you have an allergy to egg.



Allergen Encyclopedia - Egg White

Allergen Encyclopedia - Egg Yolk

Allergy UK - Egg Allergy

Anaphylaxis Campaign - Egg Allergy

FARE (US) Egg Allergy

Healthline - FODMAP Foods

Articles and Journals

Extensive boiling strongly reduces egg white allergenicity due to ovomucoid aggregation, as determined by high-resolution mass spectrometry, 2024

Vaccination and egg allergy - Considerations for family physicians, 2024

Allergy to Egg Yolk - Case Report and Literature Review, 2023

Tolerance to heated egg in egg allergy: Explanations and implications for prevention and treatment

Diagnostic utility of allergy tests to predict baked egg and lightly cooked egg allergies compared to double-blind placebo-controlled food challenges, 2023

Anaphylaxis to egg, through breast milk or airborne allergen? A case study, 2023

The Atypical Features of Atypical Egg Food Protein-Induced Enterocolitis (FPIES), 2023

The Precision Allergy Molecular Diagnosis (PAMD@) in Monitoring the Atopic March in a Child with a Primary Food Allergy: Case Report, 2022

Sensitivity, specificity and positive predictive value of ALEX2 multiplex examination in patients suffering from atopic dermatitis and reaction to egg, 2022

A case of food-induced acute pancreatitis in a child with egg white allergy, 2022

Early diagnosis of egg yolk-associated FPIES relates to early tolerance acquisition, 2022

Avoidance of Hen's Egg Based on IgE Levels Should Be Avoided for Children With Hen's Egg Allergy, 2021

Association between sites and severity of eczema and the onset of cow’s milk and egg allergy in children, 2020

Safe egg yolk consumption after a negative result for low‐dose egg oral food challenge, 2020

Safety of Measles, Mumps, and Rubella Vaccine in Egg Allergy: in Vivo and in Vitro Management, 2020

Influenza vaccine recommendations for children with egg allergy, 2018

Tolerance of a high-protein baked-egg product in egg-allergic children, 2016

Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up, 2015

Allergenicity of pasteurized whole raw Hen's egg compared with fresh whole raw Hen's egg, 2015

Cracking the egg: An insight into egg hypersensitivity, 2015

Egg Food Challenges are Associated with More Gastrointestinal Reactions, 2015

Factors associated with the course of egg allergy in children, 2015

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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