Key Allergens

Peaches are in the Rosaceae family of plants which also includes almonds, apples, plums, pears and cherries.

Most people suffering oral allergy type symptoms to peach are thought to be sensitised to the protein Pru p 1, which is similar in shape to Bet v 1 which is a protein found in birch pollen. This can cause cross reactions with other fruit.

Pru p 2 is a thaumatin-like protein, this is made by plants to inhibit fungal growth.

Pru p 3 is a Lipid Transfer Protein (LTP), these proteins are resistant to heat and are found in many types of plants. Patients suffering from a more severe allergy to cooked fruit may be sensitised to this group of proteins.

Pru p 4 is a profilin protein, these proteins are considered to be panallergens and can cause issues over many groups of foods.

Pru p 7 is a gibberellin regulated protein. Gibberellins are plant hormones associated with growth and development.

Food Intolerances

Food is high in FODMAP Food is high in salicylates

Peaches are a high FODMAP food. FODMAP stands for Fermentable oligosaccharides, disaccharides, monosaccharides and polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.

Peaches are a food high in salicylates. Salicylates have the potential to cause worsening of asthma, swelling, itching and hives as well as food intolerance symptoms in people who are sensitive to salicylates.

You can read more about Food Intolerances on the dedicated Food Intolerance Page.

Associated Syndromes

You may have Pollen-Food Allergy Syndrome if you suffer from peach allergy with oral allergy symptoms to 3 or more of the foods mentioned in cross reactivity section.

You may be suffering from LTP Syndrome if you suffer allergic reactions from eating 3 or more foods mentioned in the cross reactivity section below.

Allergy to peach is sometimes linked to Celery-Mugwort-Spice Syndrome as the sensitising allergen is a profilin protein called Art v 4, these proteins are also sometimes also called Bet v 2 proteins.

There is a link between peach and Latex Food Syndrome. The plant involved in latex allergy Hevea brasiliensis, the rubber tree plant, has an allergen called Hev b 8 which is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases.

Cross Reactivity

If sensitised to alder tree pollen you may have Pollen Food Allergy Syndrome and may also react to apple, peach, pear, parsley, celery, almonds and hazelnuts.

If sensitised to birch tree pollen you may have Pollen Food Allergy Syndrome and may also react to kiwi, pear, peach, plum, nectarine, apricots, apple, tomato, celery, carrot, potato, parsnip, pepper, dill, cumin, peas, coriander, fennel, hazelnut, walnut, almonds, peanuts, lentils and beans.

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.

Other foods containing thaumatin proteins are kiwi, chilli, peppers, apple, banana, cherry and peach.

Other foods containing plant profilins are carrot, kiwi, pineapple, celery, peanut, chilli, watermelon, orange, hazelnut, melon, strawberry, soya, barley, walnut, lychee, lupin, apple, banana, date, cherry, almond, peach, pear, mustard, tomato, aubergine and wheat.

Gibberellin regulated proteins are also found in chilli, cherry, apricots, oranges and pomegranate.



Allergen Encyclopedia - Peach

DermNet NZ - Pollen Food Allergy Syndrome

British Dietetic Association - PFAS vs LTP Syndrome

Lipid Transfer Proteins (LTP Syndrome)

OAS – When Raw Fruit is Forbidden

Allergy information for: Peach (Prunus persica)

Allergy to Fruit - Anaphylaxis Campaign

Allergy UK - Oral Allergy Syndrome

Patient UK - Oral Allergy Syndrome

Healthline - FODMAP Foods

ATP Science - Salicylate Foods

Articles and Journals

R-mandelonitrile-lyase, homolog to Pru d 10, is a major peach allergen in peach allergic Spanish population, 2024

High pan-allergen content in mango and peach in Taiwan, 2023

Immunotherapy with Pru p 3 for food allergy to peach and non-specific lipid transfer protein: a systematic review, 2023

Peach extract induces systemic and local immune responses in an experimental food allergy model, 2023

Natural Tolerance Development to Peach in a Child with Lipid Transfer Protein Allergy, 2022

Capsicum Allergy: Involvement of Cap a 7, a New Clinically Relevant Gibberellin-Regulated Protein Cross-Reactive With Cry j 7, the Gibberellin-Regulated Protein From Japanese Cedar Pollen, 2022

Subjects develop tolerance to Pru p 3 but respiratory allergy to Pru p 9: A large study group from a peach exposed population, 2021

The Role of Lipid Transfer Proteins as Food and Pollen Allergens Outside the Mediterranean Area, 2021

Pollen-food allergy syndrome in children, 2020

Phenotyping peach‐allergic patients sensitized to LTP and analysing severity biomarkers, 2020

Pru p 7 sensitization is a predominant cause of severe, cypress pollen‐associated peach allergy, 2019

Lipid Transfer Protein allergy in the United Kingdom: Characterization and comparison with a matched Italian cohort, 2019

Different co-sensitizations could determine different risk assessment in peach allergy? Evaluation of an anaphylactic biomarker in Pru p 3 positive patients, 2015

The Involvement of Thaumatin-Like Proteins in Plant Food Cross-Reactivity: A Multicenter Study Using a Specific Protein Microarray, 2012

Characterization of peach thaumatin-like proteins and their identification as major peach allergens, 2010

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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